Effect of prior cancer history on survival of patients with esophageal carcinoma: a propensity score matching, population-based study.

ABSTRACT:

Background

When conducting esophageal cancer clinical trials, prior cancer history is frequently considered an exclusion criterion due to the assumption that prior malignancy may exert significant interference with the prognosis in patients with esophageal carcinoma. This study aimed to evaluate the impact of prior cancer on survival of patients with esophageal cancer and provide valuable assistance for trial design.

Methods

Data regarding patients diagnosed with esophageal cancer between 2011 and 2016 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database and divided into two groups depending on the presence or absence of prior cancer history. Propensity score matching (PSM) was performed to minimize the confounding bias caused by covariates. Su

SUBMITTER: Liu J 

PROVIDER: S-EPMC9096290 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature