Interstitial lung disease and wedge resection are poor prognostic factors for non-small cell lung cancer.

ABSTRACT:

Background

Although several prognostic factors in patients undergoing pulmonary resection with early-stage non-small cell lung cancer (NSCLC) have been reported, the risk factors are varied and have not been consistent among reports.

Methods

Clinical data of 540 patients with pathological stage IA NSCLC were analyzed. Patient factors, such as the sex, age, comorbidities, carcinoembryonic antigen (CEA) level, and smoking history, and surgical factors, such as the operative approach and procedure, were collected and analyzed.

Results

There were significant prognostic differences in the relapse-free survival (RFS) depending on the presence of interstitial lung disease (P<0.0001), CEA level (P=0.007), and wedge resection (P=0.002). There were significant prognostic differ

SUBMITTER: Motono N 

PROVIDER: S-EPMC9096310 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature