Predictors of high flow oxygen therapy failure in COVID-19-related severe hypoxemic respiratory failure.

ABSTRACT:

Background

During COVID-19 pandemic, people who developed pneumonia and needed supplemental oxygen, where treated with low-flow oxygen therapy systems and non-invasive methods, including oxygen therapy using high flow nasal cannula (HFNC) and the application of bi-level or continuous positive airway pressure (BiPAP or CPAP). We aimed to investigate the outcomes of critical COVID-19 patients treated with HFNC and unveil predictors of HFNC failure.

Methods

We retrospectively enrolled patients admitted to COVID-19 wards and treated with HFNC for COVID-19-related severe hypoxemic respiratory failure. The primary outcome of this study was treatment failure, such as the composite of intubation or death during hospital stay. The association between treatment failure and clinical fe

SUBMITTER: Polydora E 

PROVIDER: S-EPMC9096326 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature