Neoadjuvant radiotherapy for soft tissue sarcoma in China: a preliminary result.

ABSTRACT:

Background

Neoadjuvant radiotherapy (RT) for soft tissue sarcoma (STS) is widely used abroad, but rarely reported in China. We assessed the preliminary clinical outcomes of preoperative RT followed by surgery in patients with STS.

Methods

A total of 19 patients (14 male, 5 female) with intermediate- or high-grade primary STS were treated with neoadjuvant RT in 2-Gy fractions over 25 sessions for a total dose of 50 Gy. Surgical resection was then performed. The pathologic specimens were reviewed for percentage of residual tumor cells. And the skin complications, wound complications and local recurrence and distant metastasis were also evaluated.

Results

After neoadjuvant RT, 2 patients had progressive disease (PD), 6 showed a partial remission (PR), and 11 demonstrated

SUBMITTER: Huang Z 

PROVIDER: S-EPMC9096360 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature