Postdialysis serum phosphate equilibrium in hemodialysis patients on a controlled diet and no binders.

ABSTRACT:

Background

Studies evaluating the change in serum phosphate post hemodialysis (HD) demonstrate an initial decline during dialysis but a rebound post dialysis. However, previous studies were done on usual diet and phosphate binders, with limited number of blood draws, confounding conclusions. We determined serum phosphate reduction, rebound, and equilibrium over 48 h in HD patients consuming a controlled, low phosphorus diet without binders.

Methods

Serum phosphate (mg/dL) was analyzed before and after a HD treatment and frequently during the ensuing 48 h intradialytic period in the clinical research unit. Thirteen subjects were enrolled and had been off phosphate binders for 10 days and consumed a standardized low phosphate (900 mg/day) diet for 3 weeks prior to the assessme

SUBMITTER: Stremke ER 

PROVIDER: S-EPMC9096807 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature