The severity of portal hypertension by a non-invasive assessment: acoustic structure quantification analysis of liver parenchyma.

ABSTRACT:

Background

Acoustic structure quantification (ASQ) has been applied to evaluate liver histologic changes by analyzing the speckle pattern seen on B-mode ultrasound. We aimed to assess the severity of portal hypertension (PHT) through hepatic ultrasonography.

Methods

Sixty patients diagnosed with PHT and underwent surgical treatment with portosystemic shunts were enrolled. Portal pressure (PP) was measured intraoperatively. Patients were divided into subgroups according to the severity of gastroesophageal varices and Child-Pugh class. Three difference ratio (C_m²) values on ASQ histogram mode were analyzed for their relationships with PP, degree of gastroesophageal varices and Child-Pugh liver function. Thirty healthy volunteers matched with the patients

SUBMITTER: Cai WB 

PROVIDER: S-EPMC9097305 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature