Ewe breed differences in the cervical transcriptome at the follicular phase of a synchronised oestrous cycle.

ABSTRACT:

Background

Cervical artificial insemination (AI) with frozen-thawed semen results in unacceptably low pregnancy rates internationally. The exception is in Norway, where vaginal deposition of frozen-thawed semen to a natural oestrous routinely yields pregnancy rates in excess of 70%. Previous studies by our group has demonstrated that this is due to differences in cervical sperm transport. However, a potentially important contributory factor is that ewes are inseminated to a natural oestrous in Norway but to a synchronised oestrous across most of the rest of the world. In this study, we interrogated the gene expression of the sheep cervix of four ewe breeds with known differences in pregnancy rates following cervical AI using frozen-thawed semen under the effect of exogenous hormone

SUBMITTER: Abril-Parreno L 

PROVIDER: S-EPMC9097332 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature