Hemoperfusion: technical aspects and state of the art.

ABSTRACT:

Background

Blood purification through the removal of plasma solutes by adsorption to beads of charcoal or resins contained in a cartridge (hemoperfusion) has a long and imperfect history. Developments in production and coating technology, however, have recently increased the biocompatibility of sorbents and have spurred renewed interest in hemoperfusion.

Methods

We performed a narrative assessment of the literature with focus on the technology, characteristics, and principles of hemoperfusion. We assessed publications in ex vivo, animal, and human studies. We synthesized such literature in a technical and state-of-the-art summary.

Results

Early hemoperfusion studies were hampered by bioincompatibility. Recent technology, however, has improved its safety. Hemoperfusion

SUBMITTER: Ronco C 

PROVIDER: S-EPMC9097563 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature