Household Transmission and Clinical Features of SARS-CoV-2 Infections.

ABSTRACT:

Objectives

Examine age differences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission risk from primary cases and infection risk among household contacts and symptoms among those with SARS-CoV-2 infection.

Methods

People with SARS-CoV-2 infection in Nashville, Tennessee and central and western Wisconsin and their household contacts were followed daily for 14 days to ascertain symptoms and secondary transmission events. Households were enrolled between April 2020 and April 2021. Secondary infection risks (SIR) by age of the primary case and contacts were estimated using generalized estimating equations.

Results

The 226 primary cases were followed by 198 (49%) secondary SARS-CoV-2 infections among 404 household contacts. Age group-specific SIR

SUBMITTER: McLean HQ 

PROVIDER: S-EPMC9097956 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature