The Relationship Between Short-Term Mean Arterial Pressure Variability and Mortality in Critically Ill Patients.

ABSTRACT:

Background

Increased or decreased blood pressure variability may affect the perfusion of tissues and organs, leading to acute kidney injury and death. This study was conducted to explore the relationship between mean arterial pressure variability and short- and long-term mortality in critically ill patients.

Methods

We used patient data from the MIMIC-III database for cohort study. According to the recorded mean arterial pressure during the first 24 h in the intensive care unit, we calculated each patient's two variability parameters -coefficient of variation and average real variability. The primary outcome was in-hospital mortality and the secondary outcomes were 28-day mortality and 1-year mortality. We conducted smooth spline models to examine the possible nonlinear asso

SUBMITTER: Hou C 

PROVIDER: S-EPMC9099027 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature