Association of Blood Glucose Level and Glycemic Variability With Mortality in Sepsis Patients During ICU Hospitalization.

ABSTRACT:

Background

There was considerable debate regarding the effect of mean blood glucose (MBG) and glycemic variability (GV) on the mortality of septic patients. This retrospective cohort study aimed to assess the association between MBG and GV with ICU mortality of sepsis patients and to explore the optimal MBG range.

Methods

Sepsis patients were enrolled from the Medical Information Mart for Intensive Care IV database (MIMIC-IV). MBG and glycemic coefficient of variation (Glu_CV) were, respectively, calculated to represent the overall glycemic status and GV during ICU stay. The associations between MBG, Glu_CV, and ICU mortality of the septic patients were assessed by using multivariate logistic regression in different subgroups and the severity of sepsis. R

SUBMITTER: Lu Z 

PROVIDER: S-EPMC9099235 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature