Association of Thyroid Hormone Treatment Intensity With Cardiovascular Mortality Among US Veterans.

ABSTRACT:

Importance

Cardiovascular disease is the leading cause of death in the United States. Synthetic thyroid hormones are among the 3 most commonly prescribed medications, yet studies evaluating the association between the intensity of thyroid hormone treatment and cardiovascular mortality are scarce.

Objective

To evaluate the association between thyroid hormone treatment intensity and cardiovascular mortality.

Design, setting, and participants

This retrospective cohort study used data on 705 307 adults who received thyroid hormone treatment from the Veterans Health Administration Corporate Data Warehouse between January 1, 2004, and December 31, 2017, with a median follow-up of 4 years (IQR, 2-9 years). Two cohorts were studied: 701 929 adults aged 18 years or older who i

SUBMITTER: Evron JM 

PROVIDER: S-EPMC9099430 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature