An Explorative Study of the Incidental High Renal Excretion of [¹⁸F]PSMA-1007 for Prostate Cancer PET/CT Imaging.

ABSTRACT: Positron emission tomography (PET) of prostate-specific membrane antigen (PSMA) allows for accurate diagnosis and staging of prostate cancer (PCa). Compared to other PSMA PET tracers available, [¹⁸F]PSMA-1007 is predominantly excreted via the hepatobiliary tract resulting in low renal excretion which improves evaluation of the pelvic area. However, some patients do show high urinary uptake of [¹⁸F]PSMA-1007. The present study aimed to investigate this sudden high urinary uptake of [¹⁸F]PSMA-1007 by evaluating [¹⁸F]PSMA-1007 PET scans from PCa patients. In this single-center retrospective study, patients that underwent [¹⁸F]PSMA-1007 PET imaging between July 2018 and January 2021 were included. Data regarding the individual patient char

SUBMITTER: Allach Y 

PROVIDER: S-EPMC9100267 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature