Impacts of seasonality on gene expression in the Chinese horseshoe bat.

ABSTRACT: Seasonality can cause changes in many environmental factors which potentially affects gene expression. Here, we used a bat species (Rhinolophus sinicus) from eastern China as a model to explore the molecular mechanisms of seasonal effects, in particular during phenological shifts in the spring and autumn. Based on the analysis of 45 RNA-seq samples, we found strong seasonal effects on gene expression, with a large number of genes identified as either specific or biased to each season. Weighted gene co-expression network analysis also identified multiple modules significantly associated with each season. These seasonal genes were further enriched into different functional categories. Consistent with effects of phenological shifts on bats, we found that genes related to promoting food

SUBMITTER: Chen W 

PROVIDER: S-EPMC9100453 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature