Machine learning for the prediction of acute kidney injury in patients with sepsis.

ABSTRACT:

Background

Acute kidney injury (AKI) is the most common and serious complication of sepsis, accompanied by high mortality and disease burden. The early prediction of AKI is critical for timely intervention and ultimately improves prognosis. This study aims to establish and validate predictive models based on novel machine learning (ML) algorithms for AKI in critically ill patients with sepsis.

Methods

Data of patients with sepsis were extracted from the Medical Information Mart for Intensive Care III (MIMIC- III) database. Feature selection was performed using a Boruta algorithm. ML algorithms such as logistic regression (LR), k-nearest neighbors (KNN), support vector machine (SVM), decision tree, random forest, Extreme Gradient Boosting (XGBoost), and artificial neural netw

SUBMITTER: Yue S 

PROVIDER: S-EPMC9101823 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature