Ontology highlight
ABSTRACT:
SUBMITTER: Larsson SC
PROVIDER: S-EPMC9102212 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Larsson Susanna C SC Woolf Benjamin B Gill Dipender D
Nutrients 20220419 9
We leveraged genetic variants associated with caffeine metabolism in the two-sample Mendelian randomization framework to investigate the effect of plasma caffeine levels on the risk of Alzheimer's disease and Parkinson's disease. Genetic association estimates for the outcomes were obtained from the International Genomics of Alzheimer's Project, the International Parkinson's Disease Genomics consortium, the FinnGen consortium, and the UK Biobank. Genetically predicted higher plasma caffeine level ...[more]