The Novodiag^® Stool parasites assay, an innovative high-plex technique for fast detection of protozoa, helminths and microsporidia in stool samples: a retrospective and prospective study.

ABSTRACT:

Objectives

We provide the first evaluation of the CE-IVD marked Novodiag^® stool parasites assay (NVD), allowing rapid and high-plex detection of 26 distinct targets, encompassing protozoans, helminths and microsporidia in stool samples.

Methods

A total of 254 samples (n = 205 patients) were prospectively processed by the NVD and our routine procedure (RP). Performances of the NVD were compared with RP. Samples only positive by the NVD assay were investigated by external PCR assays. Sensitivity and specificity (Se/Sp) and time from sample receipt to results were determined for each method. The NVD was also evaluated against 77 additional samples positive for a wide range of parasites.

Results

Overall positivity rate was 16.9% for RP compared with 34% using t

SUBMITTER: Hartuis S 

PROVIDER: S-EPMC9102957 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature