Association of Two Opposing Responses Results in the Emergence of a Novel Conditioned Response.

ABSTRACT: Recent studies examining association of opposing responses, contrasting emotional valences, or counter motivational states have begun to elucidate how learning and memory processes can translate to clinical therapies for trauma or addiction. In the current study, association of opposing responses is tested in C. elegans. Due to its relatively simple and well-described nervous system, it was hypothesized that association of two oppositional stimuli presented in a delayed conditioning protocol would strengthen the behavioral response to the first stimulus (alpha conditioning). To test this, C. elegans were exposed to a tone vibration stimulus (to activate a mechanosensory-driven locomotor reversal response) paired with a blue light (to activate a forward locomotor response) at

SUBMITTER: Pribic MR 

PROVIDER: S-EPMC9102977 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature