A Model of Pattern Separation by Single Neurons.

ABSTRACT: For efficient processing, spatiotemporal spike patterns representing similar input must be able to transform into a less similar output. A new computational model with physiologically plausible parameters shows how the neuronal process referred to as "pattern separation" can be very well achieved by single neurons if the temporal qualities of the output patterns are considered. Spike patterns generated by a varying number of neurons firing with fixed different frequencies within a gamma range are used as input. The temporal and spatial summation of dendritic input combined with theta-oscillating excitability in the output neuron by subthreshold membrane potential oscillations (SMOs) lead to high temporal separation by different delays of output spikes of similar input patterns. A Winner Ta

SUBMITTER: Loffler H 

PROVIDER: S-EPMC9103200 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature