The Effect of Enteral Immunonutrition in the Intensive Care Unit: Does It Impact on Outcomes?

ABSTRACT: Background: The present research aimed to evaluate the effect on outcomes of immunonutrition (IMN) enteral formulas during the intensive care unit (ICU) stay. Methods: A multicenter prospective observational study was performed. Patient characteristics, disease severity, nutritional status, type of nutritional therapy and outcomes, and laboratory parameters were collected in a database. Statistical differences were analyzed according to the administration of IMN or other types of enteral formulas. Results: In total, 406 patients were included in the analysis, of whom 15.02% (61) received IMN. Univariate analysis showed that patients treated with IMN formulas received higher mean caloric and protein intake, and better 28-day survival (85.2% vs. 73.3%; p = 0.014. Unadjusted Hazard Ratio (HR)

SUBMITTER: Lopez-Delgado JC 

PROVIDER: S-EPMC9103218 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature