Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii.

ABSTRACT: Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action of antibiotics used against them. AR is rising to a high level across the globe, and novel resistant strains are emerging and spreading very fast. Acinetobacter baumannii is a multidrug resistant Gram-negative bacteria, responsible for causing severe nosocomial infections that are treated with several broad spectrum antibiotics: carbapenems, β-lactam, aminoglycosides, tetracycline, gentamicin, impanel, piperacillin, and amikacin. The A. baumannii genome is superplastic to acquire new resistant mechanisms and, as there is no vaccine in the development process for this pathogen, the situation is more worrisome. This study was conducted to identify protective antigens from the core ge

SUBMITTER: Ud-Din M 

PROVIDER: S-EPMC9104312 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature