Validity of the Cancer and Aging Research Group Predictive Tool in Older Japanese Patients.

ABSTRACT:

Background

This study aimed to evaluate the usefulness of the Cancer and Aging Research Group (CARG) predictive tool in older Japanese patients with cancer.

Methods

Patients aged 65 years or older with solid tumors treated with new anticancer regimens in Kakogawa Central City Hospital between April 2016 and March 2019 were included. Grade 3 or higher risks of developing chemotherapy-related adverse events (CRAEs) were calculated using the tool (low-, intermediate-, or high-risk scores). The association between grade 3-5 CRAE incidence during the first course of each regimen and the calculated risk or the patient characteristics was evaluated. The difference in the incidences of CRAEs between the groups was evaluated by Fisher's exact test.

Results

This study examined

SUBMITTER: Suto H 

PROVIDER: S-EPMC9104937 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature