Maternal Iodine Intake and Neurodevelopment of Offspring: The Japan Environment and Children's Study.

ABSTRACT: Inadequate maternal iodine intake affects thyroid function and may impair fetal brain development. This study investigated the association between maternal iodine intake during pregnancy and neurodevelopmental delay in offspring at 1 and 3 years of age using a nationwide birth cohort: the Japan Environment and Children's Study. We assessed dietary iodine intake during pregnancy using a food frequency questionnaire and child neurodevelopment using the Japanese translation of the Ages and Stages Questionnaire, Third Edition. The risk of delay (score below the cut-off value) for fine motor domain at 1 year of age was increased in the lowest quintile iodine intake group compared with the fourth quintile iodine intake group. The risk of delay for problem-solving at 1 year of age was increased i

SUBMITTER: Hisada A 

PROVIDER: S-EPMC9105063 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature