Biological Activities of Some Isoquinoline Alkaloids from Fumaria schleicheri Soy. Will.

ABSTRACT: Fumaria schleicheri Soy. Will. is a species belonging to the Papaveraceae family, being widespread in East-Central and Southern Europe. As with numerous other species of the genus, it is used in traditional medicine for the treatment of hepatobiliary and digestive disorders. The aim of the present study consisted of the evaluation of its alkaloid content and the assessment of its in vitro antioxidant, anti-cholinesterase and cytotoxic potential. Total alkaloid content in the composition of the species was quantified by a spectrophotometrical method and they were individually identified and quantified by HPLC-DAD. The antioxidant capacity was investigated by the DPPH and FRAP methods, while the anti-cholinesterase activity was assessed by an adapted Ellman's method. The in vitro cyto

SUBMITTER: Paltinean R 

PROVIDER: S-EPMC9105361 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature