Analysis of Plant-Plant Interactions Reveals the Presence of Potent Antileukemic Compounds.

ABSTRACT: A method to identify anticancer compounds in plants was proposed based on the hypothesis that these compounds are primarily present in plants to provide them with an ecological advantage over neighboring plants and other competitors. According to this view, identifying plants that contain compounds that inhibit or interfere with the development of other plant species may facilitate the discovery of novel anticancer agents. The method was developed and tested using Magnolia grandiflora, Gynoxys verrucosa, Picradeniopsis oppositifolia, and Hedyosmum racemosum, which are plant species known to possess compounds with cytotoxic activities. Plant extracts were screened for growth inhibitory activity, and then a thin-layer chromatography bioautography assay was conduct

SUBMITTER: Mery DE 

PROVIDER: S-EPMC9105371 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature