Validation of Friedewald, Martin-Hopkins and Sampson low-density lipoprotein cholesterol equations.

ABSTRACT:

Background

Low-density lipoprotein cholesterol (LDL-C) is an important biomarker for determining cardiovascular risk and regulating lipid lowering therapy. Therefore, the accurate estimation of LDL-C concentration is essential in cardiovascular disease diagnosis and prognosis. Sampson recently proposed a new formula for the estimation of LDL-C. However, little is known regarding the validation of this formula.

Objectives

This study aimed to validate this new formula with other well-known formulas in Turkish population, composed of adults.

Methods

A total of 88,943 participants above 18 years old at Sivas Cumhuriyet University Hospital (Sivas, Turkey) were included to this study. LDL-C was directly measured by homogeneous assays, i.e., Roche, Beckman and Siemens and es

SUBMITTER: Erturk Zararsız G 

PROVIDER: S-EPMC9106156 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature