Association between pre-pregnancy multimorbidity and adverse maternal outcomes: A systematic review.

ABSTRACT:

Objective

We reviewed the literature on the association between pre-pregnancy multimorbidity (co-occurrence of two or more chronic conditions) and adverse maternal outcomes in pregnancy and postpartum.

Data sources

Medline, EMBASE, and CINAHL were searched from inception to September, 2021.

Study selection

Observational studies were eligible if they reported on the association between ≥ 2 co-occurring chronic conditions diagnosed before conception and any adverse maternal outcome in pregnancy or within 365 days of childbirth, had a comparison group, were peer-reviewed, and were written in English.

Data extraction and synthesis

Two reviewers used standardized instruments to extract data and rate study quality and the certainty of evidence. A narrative synthesis

SUBMITTER: Brown HK 

PROVIDER: S-EPMC9106308 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature