Efficacy of specimen pasting after cold snare polypectomy for pathological evaluation of horizontal margins.

ABSTRACT: Background and study aims  Several studies have reported that pathological horizontal margin evaluation cannot be diagnosed in cold snare polypectomy (CSP) specimens. We conducted a prospective randomized controlled trial to determine the efficacy of pasting CSP specimens on paper for pathological horizontal margins. Patients and methods  This was a single-center, prospective study conducted at Osaka Saiseikai Nakatsu Hospital. In this study, the indications for CSP were adenomas ≤ 10 mm. Colorectal polyps resected by CSP were randomized to the pasting and non-pasting groups after exclusion of fragmented specimens, and the extended CSP specimens pasted on paper were formalin-fixed in the pasting group. The primary endpoint was rate of unclear horizontal margins after CSP.

SUBMITTER: Ikeda T 

PROVIDER: S-EPMC9106410 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature