The DONALD study as a longitudinal sensor of nutritional developments: iodine and salt intake over more than 30 years in German children.

ABSTRACT:

Purpose

Mild-to-moderate iodine deficiency was present in large parts of Germany up to the beginning 1990s and improved from then on. Current epidemiological data on spot urine iodine measurements in German children strongly suggest the re-occurrence of an impaired iodine status. We thus examined whether this re-occurrence is identifiable in more detail, through iodine analyses of 24-h urine samples of a well-characterized cohort of German children in whom samples have been systematically collected from 1985 onward. As iodized salt is a major source for iodine supply, urinary sodium excretion was additionally studied.

Methods

Daily iodine and sodium excretions were measured in 2600 24-h urine samples collected between 1985 and 2018 by 677 healthy children aged 6-12 years (pa

SUBMITTER: Remer T 

PROVIDER: S-EPMC9106614 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature