A colorimetric electronic tongue for point-of-care detection of COVID-19 using salivary metabolites.

ABSTRACT: The monitoring of profile concentrations of chemical markers in saliva samples can be used to diagnose COVID-19 patients, and differentiate them from healthy individuals. Here, this purpose is achieved by designing a paper-based colorimetric sensor with an origami structure, containing general receptors such as pH-sensitive organic dyes, Lewis donors or acceptors, functionalized nanoparticles, and ion metal complexes. The color changes taking place in the receptors in the presence of chemical markers are visually observed and recorded with a digital instrument. Different types and amounts of the chemical markers provide the sensor with a unique response for patients (60 samples) or healthy (55 samples) individuals. These two categories can be discriminated with 84.3% accuracy. This study e

SUBMITTER: Bordbar MM 

PROVIDER: S-EPMC9107099 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature