Factors associated with serum CA125 level in women without ovarian cancer in the United States: a population-based study.

ABSTRACT:

Background

Cancer antigen 125 (CA125) is clinically used to monitor response to therapy in ovarian cancer and has been proposed for use in detecting ovarian cancer. This population-based study examines how demographic characteristics, gynecologic/reproductive history, chronic non-malignant medical conditions, history of non-ovarian cancer, lifestyle practices, and biomarkers of inflammation correlate with serum CA125 in both premenopausal and postmenopausal women without ovarian cancer across the United States.

Methods

Participants were identified from the National Health and Nutrition Examination Survey 2001-2002. Linear and logistic regression models were applied.

Results

Higher CA125 levels were found to correlate with younger age, Non-Hispanic White race/ethnicity

SUBMITTER: Hu X 

PROVIDER: S-EPMC9107191 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature