The colors of our brain: an integrated approach for dimensionality reduction and explainability in fMRI through color coding (i-ECO).

ABSTRACT: Several systematic reviews have highlighted the role of multiple sources in the investigation of psychiatric illness. For what concerns fMRI, the focus of recent literature preferentially lies on three lines of research, namely: functional connectivity, network analysis and spectral analysis. Data was gathered from the UCLA Consortium for Neuropsychiatric Phenomics. The sample was composed by 130 neurotypicals, 50 participants diagnosed with Schizophrenia, 49 with Bipolar disorder and 43 with ADHD. Single fMRI scans were reduced in their dimensionality by a novel method (i-ECO) averaging results per Region of Interest and through an additive color method (RGB): local connectivity values (Regional Homogeneity), network centrality measures (Eigenvector Centrality), spectral dimensions (fract

SUBMITTER: Tarchi L 

PROVIDER: S-EPMC9107439 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature