Having a stimulating lifestyle is associated with maintenance of white matter integrity with age.

ABSTRACT: Brain maintenance refers to the fact that some older adults experience few age-related changes in the brain, which helps maintain their cognition. The goal of this study was to assess maintenance of white matter integrity by testing whether reserve proxies, measuring factors associated to a stimulating lifestyle, affect the maintenance of white matter integrity. Another goal was to measure whether maintenance of white matter integrity explains inter-individual differences in working memory (WM). Forty-one cognitively healthy older adults received a structural magnetic resonance imaging (MRI) examination to measure white matter lesions. They completed an n-back WM task with different loads (1- & 2-back), along with a questionnaire on their lifestyle. There was a positive association between

SUBMITTER: Ducharme-Laliberte G 

PROVIDER: S-EPMC9107451 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature