Ontology highlight
ABSTRACT: Background
Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed attention has arisen due to recent advancements in cancer diagnostics including access to high-throughput sequencing of tumour tissue. Targeted therapies interfering with cancer specific pathways have been developed and approved for subgroups of patients. These drugs might just as well be efficient in other diagnostic subgroups, not investigated in pharma-led clinical studies, but their potential use on new indications is never explored due to limited number of patients.Methods
In this national, investigator-initiated, prospective, open-label, non-randomized
SUBMITTER: Helland A
PROVIDER: S-EPMC9107632 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature