Developing a Core Outcome Set for Clinical Trials of Chinese Medicine for Hyperlipidemia.

ABSTRACT: Background: Chinese medicine (CM) is widely used for treating hyperlipidemias, especially in China. However, the heterogeneity of outcomes measured and reported across trials exacerbates the obstacles of evidence synthesis and effectiveness comparison. In this study, we develop a core outcome set (COS) for CM clinical trials for hyperlipidemia (COS-CM-Hyperlipidemia) to tackle the outcome issues. Methods: We generated candidate outcomes through a systematic review of interventional and observational studies of Chinese medicine for hyperlipidemias. The comprehensive search strategy was employed. Study selection and data collection were independently done by two researchers. We searched clinical trial registry platform to supplement the outcomes list extracted by systematic rev

SUBMITTER: Li G 

PROVIDER: S-EPMC9108338 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature