Genetic prescreening of a candidate for laser refractive surgery identifies risk for inadequate tissue response: a case report.

ABSTRACT:

Background

Inadequate response to corneal laser refractive surgery, e.g., ectatic corneal diseases, may not be identified by conventional examinations, hence creating therapeutic uncertainty. Herein we demonstrate the application of genetic prescreening to augment preassessment for corneal laser refractive surgery and highlight the ability to prevent the possibility of enrolling a subject at risk for developing ectatic corneal diseases.

Case presentation

Preoperative tests were performed alongside deoxyribonucleic acid (DNA) sequencing of 75 genes specific to the structure and health of the eye of a 44-year-old Caucasian male candidate for corneal laser refractive surgery. The patient had no medical, family, or psychosocial history, nor symptoms that could lead to suspect an

SUBMITTER: Cusumano A 

PROVIDER: S-EPMC9109339 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature