The mean platelet volume and atherosclerotic cardiovascular-risk factors in adults with obesity: a systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Obesity is a major risk factor for atherosclerotic cardiovascular disease (ASCVD) and is associated with altered platelet function. The mean platelet volume (MPV) is a rapid measure of platelet activation and a prognostic marker in patients with cardiovascular disease. However, no meta-analysis on the association between MPV and obesity has been conducted, and the value of monitoring the MPV in patients with obesity remains unclear.

Objective

To provide cumulative evidence on whether the mean platelet volume (MPV) is increased in individuals with obesity and to describe associations between the ASCVD-risk factors and the MPV in individuals with obesity.

Methods

This meta-analysis was prepared following the Meta-analysis Of Observational Studies (MOOSE) guid

SUBMITTER: Nkambule BB 

PROVIDER: S-EPMC9109381 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature