Atopic Dermatitis and Skin Cancer Risk: A Systematic Review.

ABSTRACT:

Introduction

Atopic dermatitis (AD) is one of the most common skin diseases, and it may be associated with skin cancer risk. However, there is a controversy pertaining to whether it implies a greater or decreased risk of skin cancers. We aimed to study the relationship between AD and skin cancer risk.

Methods

PubMed and Embase databases from their inception to 4 August 2021 were systematically searched.

Results

We evaluated 16 studies involving a total of 9,638,093 participants examining the contribution of AD to skin cancers. Random-effects model was applied to estimate the overall effect sizes. The pooled analysis of 16 studies indicated that AD was significantly associated with an overall increased risk of skin cancer. Subgroup pooled analyses showed that AD was st

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC9110609 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature