Association Between Endometriosis and Subsequent Risk of Sjogren's Syndrome: A Nationwide Population-Based Cohort Study.

ABSTRACT:

Objective

The relationship between endometriosis and the ensuing risk of Sjögren's syndrome has remained unclear. This study aims to present epidemiological evidence for this connection.

Methods

This is a retrospective cohort study of endometriosis patients (ICD-9-CM 617.0-617.9 and 621.3) and matched comparison group between 2000 and 2012 in the National Taiwan Insurance Research Database. After age matching, we analyzed the association between endometriosis and Sjögren's syndrome (ICD-9-CM 710.2). We used the Cox proportional hazard model to examine the hazard ratio of incidental Sjögren's syndrome. Subgroup analyses on age, comorbidities, and disease duration were also performed.

Results

A total of 73,665 individuals were included in this study. We identified 14733

SUBMITTER: Chao YH 

PROVIDER: S-EPMC9110644 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature