Paediatric critical COVID-19 and mortality in a multinational prospective cohort.

ABSTRACT:

Background

To understand critical paediatric coronavirus disease 2019 (COVID-19) and evaluate factors associated with mortality in children from high and low-middle income countries.

Methods

Prospective, observational study of critically ill children hospitalised for COVID-19 in 18 countries throughout North America, Latin America, and Europe between April 1 and December 31, 2020. Associations with mortality were evaluated using logistic regression.

Findings

557 patients (median age, 8 years; 24% <2 years) were enrolled from 55 sites (63% Latin American). Half had comorbidities. Invasive (41%) or non-invasive (20%) ventilation and vasopressors (56%) were the most common support modalities. Hospital mortality was 10% and higher in children <2 years old (15%; odds ratio

SUBMITTER: Gonzalez-Dambrauskas S 

PROVIDER: S-EPMC9111167 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature