Episodic Past, Future, and counterfactual thinking in Relapsing-Remitting Multiple sclerosis.

ABSTRACT: Multiple sclerosis (MS) is a progressive disease characterized by widespread white matter lesions in the brain and spinal cord. In addition to well-characterized motor deficits, MS results in cognitive impairments in several domains, notably in episodic autobiographical memory. Recent studies have also revealed that patients with MS exhibit deficits in episodic future thinking, i.e., our capacity to imagine possible events that may occur in our personal future. Both episodic memory and episodic future thinking have been shown to share cognitive and neural mechanisms with a related kind of hypothetical simulation known as episodic counterfactual thinking: our capacity to imagine alternative ways in which past personal events could have occurred but did not. However, the extent to which epis

SUBMITTER: Ayala OD 

PROVIDER: S-EPMC9112031 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature