Variability independent of mean blood pressure as a real-world measure of cardiovascular risk.

ABSTRACT:

Background

Individual-level blood pressure (BP) variability, independent of mean BP levels, has been associated with increased risk for cardiovascular events in cohort studies and clinical trials using standardized BP measurements. The extent to which BP variability relates to cardiovascular risk in the real-world clinical practice setting is unclear. We sought to determine if BP variability in clinical practice is associated with adverse cardiovascular outcomes using clinically generated data from the electronic health record (EHR).

Methods

We identified 42,482 patients followed continuously at a single academic medical center in Southern California between 2013 and 2019 and calculated their systolic and diastolic BP variability independent of the mean (VIM) over the first

SUBMITTER: Ebinger JE 

PROVIDER: S-EPMC9112125 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature