Validation of the Pediatric Sequential Organ Failure Assessment Score and Evaluation of Third International Consensus Definitions for Sepsis and Septic Shock Definitions in the Pediatric Emergency Department.

ABSTRACT:

Importance

Pediatric sepsis definitions have evolved, and some have proposed using the measure used in adults to quantify organ dysfunction, a Sequential Organ Failure Assessment (SOFA) score of 2 or more in the setting of suspected infection. A pediatric adaptation of SOFA (pSOFA) showed excellent discrimination for mortality in critically ill children but has not been evaluated in an emergency department (ED) population.

Objective

To delineate test characteristics of the pSOFA score for predicting in-hospital mortality among (1) all patients and (2) patients with suspected infection treated in pediatric EDs.

Design, setting, and participants

This retrospective cohort study took place from January 1, 2012, to January 31, 2020 in 9 US children's hospitals included in

SUBMITTER: Balamuth F 

PROVIDER: S-EPMC9112137 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature