Long term impact of prophylactic antibiotic use before incision versus after cord clamping on children born by caesarean section: longitudinal study of UK electronic health records.

ABSTRACT:

Objective

To investigate the impact on child health up to age 5 years of a policy to use antibiotic prophylaxis for caesarean section before incision compared with after cord clamping.

Design

Observational controlled interrupted time series study.

Setting

UK primary and secondary care.

Participants

515 945 children born in 2006-18 with linked maternal records and registered with general practices contributing to two UK primary care databases (The Health Improvement Network and Clinical Practice Research Datalink), and 7 147 884 children with linked maternal records in the Hospital Episode Statistics database covering England, of which 3 945 351 were linked to hospitals that reported the year of policy change to administer prophylactic antibiotics for caesarean

SUBMITTER: Sumilo D 

PROVIDER: S-EPMC9112858 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature