COVID-19 infection and treatment-resistant cocaine-induced pyoderma gangrenosum: A case report.

ABSTRACT:

Introduction

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis of non-infectious etiology. Cocaine-induced PG (CIPG) is a documented clinical variant.

Case presentation

We report an exceptional case of cocaine-induced PG flare unresponsive to conventional treatment in the context of positive COVID status. A 41year-old male with past medical history of recent COVID infection, pyoderma gangrenosum and chronic cocaine abuse presented with acutely worsening multifocal ulcerations covering multiple limbs approximately 30% body surface area (BSA) one day after cocaine use. After hospitalization for ten days with no improvement in cutaneous symptoms, he was transferred to a burn center for disease control with biologics.

Discussion

The previous temporal relationshi

SUBMITTER: Adams J 

PROVIDER: S-EPMC9113765 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature