Ontology highlight
ABSTRACT:
SUBMITTER: Zhang W
PROVIDER: S-EPMC9113937 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Zhang Wenqiang W Liu Ruiyu R Zhang Lin L Wang Chao C Dong Ziyan Z Feng Jiasheng J Luo Mayao M Zhang Yifan Y Xu Zhuofan Z Lv Shidong S Wei Qiang Q
Cancer gene therapy 20210423 5
Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cancer affecting many people worldwide. Although the 5-year survival rate is 65% in localized disease, after metastasis, the survival rate is <10%. Emerging evidence has shown that microRNAs (miRNAs) play a crucial regulatory role in the progression of ccRCC. Here, we show that miR-335, an anti-onco-miRNA, is downregulation in tumor tissue and inhibited ccRCC cell proliferation, invasion, and migration. Our studies further ...[more]