Inactivation of SARS-CoV-2 by a chitosan/α-Ag₂WO₄ composite generated by femtosecond laser irradiation.

ABSTRACT: In the current COVID-19 pandemic, the next generation of innovative materials with enhanced anti-SARS-CoV-2 activity is urgently needed to prevent the spread of this virus within the community. Herein, we report the synthesis of chitosan/α-Ag₂WO₄ composites synthetized by femtosecond laser irradiation. The antimicrobial activity against Escherichia coli, Methicilin-susceptible Staphylococcus aureus (MSSA), and Candida albicans was determined by estimating the minimum inhibitory concentration (MIC) and minimal bactericidal/fungicidal concentration (MBC/MFC). To assess the biocompatibility of chitosan/α-Ag₂WO₄ composites in a range involving MIC and MBC/MFC on keratinocytes cells (NOK-si), an alamarBlue™ assay and an MTT assay were carried out. The

SUBMITTER: Pereira PFS 

PROVIDER: S-EPMC9114143 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature