The Sex-Specific Impact of the FORTA (Fit-fOR-The-Aged) List on Medication Quality and Clinical Endpoints in Older Hospitalized Patients: Secondary Analysis of a Randomized Controlled Trial.

ABSTRACT:

Background

Little is known about the sex-specific impact of drug optimization tools such as the Fit fOR The Aged (FORTA) list on drug use and relevant clinical endpoints in older people.

Objective

We aimed to detect gender differences of interventional effects on medication quality and related clinical effects in the VALFORTA trial.

Patients and methods

A sex-specific analysis of data from 409 patients (147 men and 262 women, mean age 79.4 and 82.7 years, respectively) in acute geriatric care comparing the control and FORTA intervention groups was performed. Changes of the FORTA score (sum of over- and undertreatment errors per patient), the incidence of adverse drug events (ADEs) during hospitalization, and several clinically relevant endpoints [e.g., the Barthel ind

SUBMITTER: Schmitt AK 

PROVIDER: S-EPMC9114217 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature