Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality.

ABSTRACT:

Purpose

Cytomegalovirus (CMV) reactivation in immunocompetent critically ill patients is common and relates to a worsening outcome. In this large observational study, we evaluated the incidence and the risk factors associated with CMV reactivation and its effects on mortality in a large cohort of patients affected by coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU).

Methods

Consecutive patients with confirmed SARS-CoV-2 infection and acute respiratory distress syndrome admitted to three ICUs from February 2020 to July 2021 were included. The patients were screened at ICU admission and once or twice per week for quantitative CMV-DNAemia in the blood. The risk factors associated with CMV blood reactivation and its association with mortality were es

SUBMITTER: Gatto I 

PROVIDER: S-EPMC9116062 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature