Adalimumab Effect on Pain in Hidradenitis Suppurativa Patients: Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Pain is experienced by most patients with hidradenitis suppurativa (HS) and has a severe impact on their quality of life. Its management still presents a challenge. Adalimumab, a TNF-a antagonist, has shown promising results in HS-related pain reduction.

Objectives

To aggregate and synthesize all existing evidence regarding the effect of adalimumab on HS-associated pain.

Methods

We identified original controlled and uncontrolled studies with participants receiving adalimumab, which included change in pain score post-treatment compared to baseline as an end-point. We searched MEDLINE, ScienceDirect, the Cochrane Library, ClinicalTrials.gov and International Clinical Trials Registry Platform. The primary endpoint of our study was the mean change (continuous

SUBMITTER: Tsentemeidou A 

PROVIDER: S-EPMC9116545 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature